Titre :
  • Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides.
Auteur : Boverie, Stéphane ; Antoine, Marie-Hélène ; Somers, Fabian ; Becker, Bénédicte ; Sebille, Sophie ; Ouedraogo, Raogo ; Counerotte, Stéphane ; Pirotte, Bernard ; Lebrun, Philippe ; de Tullio, Pascal
Informations sur la publication : Journal of medicinal chemistry, 48, 10, (page 3492-3503)
Statut de publication : Publié, 2005-05
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Adenosine Triphosphate -- physiology
Animals
Aorta -- drug effects
Aorta -- physiology
Benzothiadiazines -- chemical synthesis
Benzothiadiazines -- chemistry
Benzothiadiazines -- pharmacology
Insulin -- secretion
Ion Channel Gating
Islets of Langerhans -- drug effects
Islets of Langerhans -- secretion
Muscle Contraction -- drug effects
Muscle, Smooth, Vascular -- drug effects
Muscle, Smooth, Vascular -- physiology
Potassium Channels -- agonists
Rats
Rats, Wistar
Structure-Activity Relationship
Vasodilator Agents -- chemical synthesis
Vasodilator Agents -- chemistry
Vasodilator Agents -- pharmacology
Note : In Vitro
Journal Article
Langue :
  • Anglais
Identificateurs : urn:issn:0022-2623 
info:doi/10.1021/jm0311339
info:pmid/15887958