Titre :
  • Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice.
Auteur : Ledent, Catherine ; Valverde, Olga ; Cossu, G ; Petitet, F ; Aubert, J F ; Beslot, F ; Böhme, Georg Andrees ; Imperato, Assunta ; Pedrazzini, T ; Roques, Bernard P ; Vassart, Gilbert ; Fratta, W ; Parmentier, Marc
Informations sur la publication : Science, 283, 5400, (page 401-404)
Statut de publication : Publié, 1999-01
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Analgesics, Opioid -- pharmacology
Animals
Behavior, Animal -- drug effects
Blood Pressure -- drug effects
Body Temperature -- drug effects
Cannabinoids -- metabolism
Cannabinoids -- pharmacology
Heart Rate -- drug effects
Mice
Mice, Knockout
Morphine -- pharmacology
Motor Activity -- drug effects
Narcotics -- pharmacology
Opioid-Related Disorders -- physiopathology
Pain Threshold -- drug effects
Receptors, Cannabinoid
Receptors, Drug -- genetics
Receptors, Drug -- physiology
Receptors, Opioid, kappa -- agonists
Receptors, Opioid, kappa -- physiology
Reinforcement (Psychology)
Substance Withdrawal Syndrome -- physiopathology
Tetrahydrocannabinol -- pharmacology
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0036-8075 
info:doi/10.1126/science.283.5400.401
info:pmid/9888857