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Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice.

par Ledent, Catherine ;Valverde, Olga;Cossu, G;Petitet, F;Aubert, J F;Beslot, F;Böhme, Georg Andrees;Imperato, Assunta;Pedrazzini, T;Roques, Bernard P;Vassart, Gilbert ;Fratta, W;Parmentier, Marc
Référence Science, 283, 5400, page (401-404)
Publication Publié, 1999-01

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Titre:	Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice.
Auteur:	Ledent, Catherine; Valverde, Olga; Cossu, G; Petitet, F; Aubert, J F; Beslot, F; Böhme, Georg Andrees; Imperato, Assunta; Pedrazzini, T; Roques, Bernard P; Vassart, Gilbert; Fratta, W; Parmentier, Marc
Informations sur la publication:	Science, 283, 5400, page (401-404)
Statut de publication:	Publié, 1999-01
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Analgesics, Opioid -- pharmacology
	Animals
	Behavior, Animal -- drug effects
	Blood Pressure -- drug effects
	Body Temperature -- drug effects
	Cannabinoids -- metabolism
	Cannabinoids -- pharmacology
	Heart Rate -- drug effects
	Mice
	Mice, Knockout
	Morphine -- pharmacology
	Motor Activity -- drug effects
	Narcotics -- pharmacology
	Opioid-Related Disorders -- physiopathology
	Pain Threshold -- drug effects
	Receptors, Cannabinoid
	Receptors, Drug -- genetics
	Receptors, Drug -- physiology
	Receptors, Opioid, kappa -- agonists
	Receptors, Opioid, kappa -- physiology
	Reinforcement (Psychology)
	Substance Withdrawal Syndrome -- physiopathology
	Tetrahydrocannabinol -- pharmacology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0036-8075
	info:doi/10.1126/science.283.5400.401
	info:scp/0033555839
	info:pmid/9888857