Titre :
  • Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
Auteur : Paschke, Ralf ; Tonacchera, Massimo ; Van Sande, Jacqueline ; Parma, Jasmine ; Vassart, Gilbert
Informations sur la publication : The Journal of clinical endocrinology and metabolism, 79, 6, (page 1785-1789)
Statut de publication : Publié, 1994-12
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Adenoma -- genetics
Adenoma -- physiopathology
Alanine -- genetics
Amino Acid Sequence
Base Sequence
Cell Line
Codon
Cyclic AMP -- metabolism
Gene Expression
Humans
Isoleucine -- genetics
Molecular Sequence Data
Mutation
Receptors, Thyrotropin -- chemistry
Receptors, Thyrotropin -- genetics
Receptors, Thyrotropin -- physiology
Structure-Activity Relationship
Threonine -- genetics
Thyroid Neoplasms -- genetics
Thyroid Neoplasms -- physiopathology
Transfection
Valine -- genetics
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0021-972X 
info:pmid/7989485