Titre:
  • Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
Auteur:Paschke, Ralf; Tonacchera, Massimo; Van Sande, Jacqueline; Parma, Jasmine; Vassart, Gilbert
Informations sur la publication:The Journal of clinical endocrinology and metabolism, 79, 6, page (1785-1789)
Statut de publication:Publié, 1994-12
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adenoma -- genetics
Adenoma -- physiopathology
Alanine -- genetics
Amino Acid Sequence
Base Sequence
Cell Line
Codon
Cyclic AMP -- metabolism
Gene Expression
Humans
Isoleucine -- genetics
Molecular Sequence Data
Mutation
Receptors, Thyrotropin -- chemistry
Receptors, Thyrotropin -- genetics
Receptors, Thyrotropin -- physiology
Structure-Activity Relationship
Threonine -- genetics
Thyroid Neoplasms -- genetics
Thyroid Neoplasms -- physiopathology
Transfection
Valine -- genetics
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0021-972X
info:scp/0028588698
info:pmid/7989485