Titre :
  • Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy.
Auteur : Rondelet, Benoît ; Kerbaul, François ; Van Beneden, Ronald ; Motte, Sophie ; Fesler, P. ; Hubloue, Ives ; Remmelink, Myriam ; Brimioulle, Serge ; Salmon, Isabelle ; Ketelslegers, Jean-Marie ; Naeije, Robert
Informations sur la publication : Circulation, 110, 15, (page 2220-2225)
Statut de publication : Publié, 2004-10
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Angiopoietins
Heart defects
Hypertension, pulmonary
Nitric oxide
Remodeling
Mots-clés MeSH : 3',5'-Cyclic-GMP Phosphodiesterases
Anastomosis, Surgical -- adverse effects
Angiopoietin-1 -- biosynthesis
Angiopoietin-1 -- genetics
Angiopoietin-1 -- physiology
Angiotensin II -- biosynthesis
Angiotensin II -- genetics
Animals
Arterioles -- ultrastructure
Bone Morphogenetic Protein Receptors, Type I
Bone Morphogenetic Protein Receptors, Type II
Cyclic Nucleotide Phosphodiesterases, Type 5
Drug Evaluation, Preclinical
Endothelin-1 -- biosynthesis
Endothelin-1 -- genetics
Gene Expression Regulation -- drug effects
Hyperplasia
Hypertension, Pulmonary -- etiology
Hypertension, Pulmonary -- metabolism
Hypertension, Pulmonary -- prevention & control
Models, Animal
Nitric Oxide Synthase -- biosynthesis
Nitric Oxide Synthase -- genetics
Nitric Oxide Synthase Type II
Phosphodiesterase Inhibitors -- pharmacology
Phosphodiesterase Inhibitors -- therapeutic use
Phosphoric Diester Hydrolases -- biosynthesis
Phosphoric Diester Hydrolases -- drug effects
Phosphoric Diester Hydrolases -- genetics
Piperazines -- pharmacology
Piperazines -- therapeutic use
Protein-Serine-Threonine Kinases -- biosynthesis
Protein-Serine-Threonine Kinases -- genetics
Protein-Serine-Threonine Kinases -- physiology
Pulmonary Artery -- surgery
Purines
RNA, Messenger -- biosynthesis
Random Allocation
Receptors, Growth Factor -- biosynthesis
Receptors, Growth Factor -- genetics
Signal Transduction -- drug effects
Subclavian Artery -- surgery
Sulfones
Sus scrofa
Vascular Endothelial Growth Factor A -- biosynthesis
Vascular Endothelial Growth Factor A -- genetics
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0009-7322 
info:doi/10.1161/01.CIR.0000143836.40431.F5
info:pii/01.CIR.0000143836.40431.F5
info:pmid/15466636