Titre:
  • Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy.
Auteur:Rondelet, Benoît; Kerbaul, François; Van Beneden, Ronald; Motte, Sophie; Fesler, P.; Hubloue, Ives; Remmelink, Myriam; Brimioulle, Serge; Salmon, Isabelle; Ketelslegers, Jean-Marie; Naeije, Robert
Informations sur la publication:Circulation, 110, 15, page (2220-2225)
Statut de publication:Publié, 2004-10
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Angiopoietins
Heart defects
Hypertension, pulmonary
Nitric oxide
Remodeling
MeSH keywords:3',5'-Cyclic-GMP Phosphodiesterases
Anastomosis, Surgical -- adverse effects
Angiopoietin-1 -- biosynthesis
Angiopoietin-1 -- genetics
Angiopoietin-1 -- physiology
Angiotensin II -- biosynthesis
Angiotensin II -- genetics
Animals
Arterioles -- ultrastructure
Bone Morphogenetic Protein Receptors, Type I
Bone Morphogenetic Protein Receptors, Type II
Cyclic Nucleotide Phosphodiesterases, Type 5
Drug Evaluation, Preclinical
Endothelin-1 -- biosynthesis
Endothelin-1 -- genetics
Gene Expression Regulation -- drug effects
Hyperplasia
Hypertension, Pulmonary -- etiology
Hypertension, Pulmonary -- metabolism
Hypertension, Pulmonary -- prevention & control
Models, Animal
Nitric Oxide Synthase -- biosynthesis
Nitric Oxide Synthase -- genetics
Nitric Oxide Synthase Type II
Phosphodiesterase Inhibitors -- pharmacology
Phosphodiesterase Inhibitors -- therapeutic use
Phosphoric Diester Hydrolases -- biosynthesis
Phosphoric Diester Hydrolases -- drug effects
Phosphoric Diester Hydrolases -- genetics
Piperazines -- pharmacology
Piperazines -- therapeutic use
Protein-Serine-Threonine Kinases -- biosynthesis
Protein-Serine-Threonine Kinases -- genetics
Protein-Serine-Threonine Kinases -- physiology
Pulmonary Artery -- surgery
Purines
RNA, Messenger -- biosynthesis
Random Allocation
Receptors, Growth Factor -- biosynthesis
Receptors, Growth Factor -- genetics
Signal Transduction -- drug effects
Subclavian Artery -- surgery
Sulfones
Sus scrofa
Vascular Endothelial Growth Factor A -- biosynthesis
Vascular Endothelial Growth Factor A -- genetics
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0009-7322
info:doi/10.1161/01.CIR.0000143836.40431.F5
info:pii/01.CIR.0000143836.40431.F5
info:scp/20844456405
info:pmid/15466636