Titre :
  • Synthesis and in vitro antitumor activity of ring C and D-substituted phenanthrolin-7-one derivatives, analogues of the marine pyridoacridine alkaloids ascididemin and meridine.
Auteur : Delfourne, Evelyne ; Kiss, Robert ; Le Corre, Laurent ; Dujols, Frederic ; Bastide, Jean ; Collignon, Françoise ; Lesur, Brigitte ; Frydman, Armand ; Darro, Francis
Informations sur la publication : Bioorganic & medicinal chemistry, 12, 15, (page 3987-3994)
Statut de publication : Publié, 2004-08
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Ascididemin
Marine alkaloids
Meridine
Pyridoacridine
Mots-clés MeSH : Acridines -- chemistry
Alkaloids -- chemical synthesis
Alkaloids -- pharmacology
Antineoplastic Agents -- chemical synthesis
Antineoplastic Agents -- pharmacology
Cell Division -- drug effects
Cell Line, Tumor
Drug Design
Drug Screening Assays, Antitumor
Heterocyclic Compounds with 4 or More Rings -- chemical synthesis
Heterocyclic Compounds with 4 or More Rings -- pharmacology
Humans
Molecular Structure
Phenanthrolines -- chemical synthesis
Phenanthrolines -- chemistry
Phenanthrolines -- pharmacology
Quinolines -- pharmacology
Structure-Activity Relationship
Note : Journal Article
Langue :
  • Anglais
Identificateurs : urn:issn:0968-0896 
info:doi/10.1016/j.bmc.2004.06.006
info:pii/S0968089604004225
info:pmid/15246075