Titre :
  • The Na+/K+-ATPase is the Achilles heel of multi-drug-resistant cancer cells.
Auteur : Mijatovic, Tatjana ; Jungwirth, Ute ; Heffeter, Petra ; Hoda, Mir Ali Reza ; Dornetshuber, Rita ; Kiss, Robert ; Berger, Walter
Informations sur la publication : Cancer letters, 282, 1, (page 30-34)
Statut de publication : Publié, 2009-09
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : 19-hydroxy-2″oxovoruscharin
Cardenolide
Multi-drug resistance (MDR)
Na+/K+-ATPase targeting
Mots-clés MeSH : Breast Neoplasms
Carcinoma, Non-Small-Cell Lung -- pathology
Carcinoma, Small Cell -- pathology
Carcinoma, Squamous Cell
Cardenolides -- pharmacology
Cell Line, Tumor -- drug effects
Cell Survival -- drug effects
Drug Resistance, Multiple -- physiology
Hela Cells -- drug effects
Humans
Hydroxyurea -- pharmacology
Ligands
Neoplasms -- drug therapy
P-Glycoprotein -- metabolism
Sodium-Potassium-Exchanging ATPase -- drug effects
Sodium-Potassium-Exchanging ATPase -- metabolism
Thiazoles -- pharmacology
Note : Journal Article
Langue :
  • Anglais
Identificateurs : urn:issn:0304-3835 
info:doi/10.1016/j.canlet.2009.02.048
info:pii/S0304-3835(09)00161-X
info:pmid/19339106