Titre :
  • 7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
Auteur : Azéma, Joëlle ; Guidetti, Brigitte ; Dewelle, Janique ; Le Calve, Benjamin ; Mijatovic, Tatjana ; Korolyov, Alexander ; Vaysse, Julie ; Malet-Martino, Myriam ; Martino, Robert ; Kiss, Robert
Informations sur la publication : Bioorganic & medicinal chemistry, 17, 15, (page 5396-5407)
Statut de publication : Publié, 2009-08
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Cancer cell lines
Fluoroquinolones
In vitro biological evaluation
Lipophilic ciprofloxacin derivatives
Mots-clés MeSH : Animals
Antineoplastic Agents -- chemistry
Antineoplastic Agents -- pharmacology
Antineoplastic Agents -- toxicity
Cell Line, Tumor
Cell Proliferation -- drug effects
Ciprofloxacin -- analogs & derivatives
Ciprofloxacin -- chemical synthesis
Ciprofloxacin -- pharmacology
Ciprofloxacin -- toxicity
Humans
Maximum Tolerated Dose
Mice
Neoplasms -- drug therapy
Piperazines -- chemical synthesis
Piperazines -- chemistry
Piperazines -- pharmacology
Piperazines -- toxicity
Note : Journal Article
Langue :
  • Anglais
Identificateurs : urn:issn:0968-0896 
info:doi/10.1016/j.bmc.2009.06.053
info:pii/S0968-0896(09)00618-X
info:pmid/19595598