Titre :
  • The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells.
Auteur : Mijatovic, Tatjana ; Op De Beeck, Anne ; Van Quaquebeke, Eric ; Dewelle, Janique ; Darro, Francis ; De Launoit, Yvan ; Kiss, Robert
Informations sur la publication : Molecular cancer therapeutics, 5, 2, (page 391-399)
Statut de publication : Publié, 2006-02
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Animals
Antineoplastic Agents -- pharmacology
Antineoplastic Agents -- therapeutic use
Carcinoma, Non-Small-Cell Lung -- drug therapy
Carcinoma, Non-Small-Cell Lung -- metabolism
Cardenolides -- pharmacology
Cardenolides -- therapeutic use
Cytoprotection -- drug effects
DNA -- metabolism
Humans
Lung Neoplasms -- drug therapy
Lung Neoplasms -- metabolism
Mice
NF-kappa B -- metabolism
Transcription Factor RelA -- metabolism
Transcription, Genetic
Up-Regulation
Xenograft Model Antitumor Assays
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1535-7163 
info:doi/10.1158/1535-7163.MCT-05-0367
info:pii/5/2/391
info:pmid/16505114