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The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells.

par Mijatovic, Tatjana ;Op De Beeck, Anne ;Van Quaquebeke, Eric ;Dewelle, Janique;Darro, Francis;De Launoit, Yvan ;Kiss, Robert
Référence Molecular cancer therapeutics, 5, 2, page (391-399)
Publication Publié, 2006-02

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Titre:	The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells.
Auteur:	Mijatovic, Tatjana; Op De Beeck, Anne; Van Quaquebeke, Eric; Dewelle, Janique; Darro, Francis; De Launoit, Yvan; Kiss, Robert
Informations sur la publication:	Molecular cancer therapeutics, 5, 2, page (391-399)
Statut de publication:	Publié, 2006-02
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Antineoplastic Agents -- pharmacology
	Antineoplastic Agents -- therapeutic use
	Carcinoma, Non-Small-Cell Lung -- drug therapy
	Carcinoma, Non-Small-Cell Lung -- metabolism
	Cardenolides -- pharmacology
	Cardenolides -- therapeutic use
	Cytoprotection -- drug effects
	DNA -- metabolism
	Humans
	Lung Neoplasms -- drug therapy
	Lung Neoplasms -- metabolism
	Mice
	NF-kappa B -- metabolism
	Transcription Factor RelA -- metabolism
	Transcription, Genetic
	Up-Regulation
	Xenograft Model Antitumor Assays
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:1535-7163
	info:doi/10.1158/1535-7163.MCT-05-0367
	info:pii/5/2/391
	info:scp/33644974357
	info:pmid/16505114