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The steroidogenic factor-1 protein is not expressed in various forms of endometriosis but is strongly present in ovarian cortical or medullary mesenchymatous cells adjacent to endometriotic foci

par Noël, Jean Christophe ;Anaf, Vincent ;Borghese, Bruno;Vaiman, Daniel;Fayt, Isabelle ;Chapron, Charles
Référence Fertility and sterility, 95, 8, page (2655-2657)
Publication Publié, 2011-06

Article révisé par les pairs

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Résumé :

Steroidogenic factor-1 (SF-1) protein expression was not observed in any form of endometriosis (peritoneal, ovarian, or deep infiltrating endometriosis), which suggests that SF-1 locally produced by endometrial or stromal cells may not play a major role in the development of endometriosis. However, the strong expression of SF-1 in cortical and medullary ovarian mesenchymatous cells may be capable of creating a favorable steroidogenic environment and the development of the disease. © 2011 by American Society for Reproductive Medicine.