Titre:
  • Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors.
Auteur:Paci, Angelo; Rezai, Keyvan; Deroussent, Alain; De Valeriola, Dominique; Re, Micheline; Weill, Sophie; Cvitkovic, Esteban; Kahatt, Carmen; Shah, Anwar; Waters, Stephen; Weems, Gary; Vassal, Gilles; Lokiec, François
Informations sur la publication:Drug metabolism and disposition, 34, 11, page (1918-1926)
Statut de publication:Publié, 2006-11
Sujet CREF:Cancérologie
MeSH keywords:Antineoplastic Agents, Alkylating -- blood -- metabolism -- pharmacokinetics -- urine
Carbon Radioisotopes
Chromatography, High Pressure Liquid
Feces -- chemistry
Female
Humans
Infusions, Intravenous
Male
Molecular Structure
Neoplasms -- drug therapy -- metabolism
Sesquiterpenes -- blood -- metabolism -- pharmacokinetics -- urine
Spectrometry, Mass, Electrospray Ionization
Tissue Distribution
Note générale:Clinical Trial, Phase I
Journal Article
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0090-9556
info:doi/10.1124/dmd.106.010512
info:pii/dmd.106.010512
info:scp/33751088563
info:pmid/16896064