Titre :
  • Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy.
Auteur : Hubaux, Roland ; Vandermeers, Fabian ; Crisanti, M Cecilia ; Crisanti, Cecilia ; Kapoor, Veena ; Burny, Arsène ; Mascaux, Céline ; Albelda, Steven M ; Willems, Lucas
Informations sur la publication : European journal of cancer, 46, 9, (page 1724-1734)
Statut de publication : Publié, 2010-06
Sujet CREF : Cancérologie
Mots-clés : Chemotherapy
HDAC
Mice
Small cell lung cancer
Valproate
Mots-clés MeSH : Animals
Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
Apoptosis -- drug effects -- genetics
Blotting, Western
Caspases -- metabolism
Cell Line, Tumor
Cell Proliferation -- drug effects
Cisplatin -- administration & dosage
Drug Synergism
Etoposide -- administration & dosage
Female
Gene Expression -- drug effects
Histone Deacetylase Inhibitors -- therapeutic use
Humans
Lung Neoplasms -- drug therapy
Mice
Mice, SCID
Microarray Analysis
Neoplasm Transplantation
Small Cell Lung Carcinoma -- drug therapy
Transplantation, Heterologous
Valproic Acid -- therapeutic use
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0959-8049 
info:doi/10.1016/j.ejca.2010.03.021
info:pii/S0959-8049(10)00252-2
info:pmid/20451370