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Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy.

par Hubaux, Roland;Vandermeers, Fabian;Crisanti, M Cecilia;Crisanti, M Cecilia;Kapoor, Veena;Burny, Arsène ;Mascaux, Céline ;Albelda, Steven Mark;Willems, Lucas
Référence European journal of cancer, 46, 9, page (1724-1734)
Publication Publié, 2010-06

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Titre:	Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy.
Auteur:	Hubaux, Roland; Vandermeers, Fabian; Crisanti, M Cecilia; Crisanti, M Cecilia; Kapoor, Veena; Burny, Arsène; Mascaux, Céline; Albelda, Steven Mark; Willems, Lucas
Informations sur la publication:	European journal of cancer, 46, 9, page (1724-1734)
Statut de publication:	Publié, 2010-06
Sujet CREF:	Cancérologie
Mots-clés:	Chemotherapy
	HDAC
	Mice
	Small cell lung cancer
	Valproate
MeSH keywords:	Animals
	Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
	Apoptosis -- drug effects -- genetics
	Blotting, Western
	Caspases -- metabolism
	Cell Line, Tumor
	Cell Proliferation -- drug effects
	Cisplatin -- administration & dosage
	Drug Synergism
	Etoposide -- administration & dosage
	Female
	Gene Expression -- drug effects
	Histone Deacetylase Inhibitors -- therapeutic use
	Humans
	Lung Neoplasms -- drug therapy
	Mice
	Mice, SCID
	Microarray Analysis
	Neoplasm Transplantation
	Small Cell Lung Carcinoma -- drug therapy
	Transplantation, Heterologous
	Valproic Acid -- therapeutic use
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0959-8049
	info:doi/10.1016/j.ejca.2010.03.021
	info:pii/S0959-8049(10)00252-2
	info:scp/77952582492
	info:pmid/20451370