Résumé : International organizations working on public health projects and programs are increasingly eager to integrate the Human-centred design approach into their interventions in order to find innovative, desirable, and contextually relevant solutions to complex and persistent public health problems. Despite this strong interest, there is very little research on the effectiveness and impacts of this approach on health outcomes. This thesis provides an anthropological study of how this approach is being implemented in the context of the "Beyond Bias" project in Burkina Faso. This case study is the result of 4 months of fieldwork, during which I actively participated in the implementation of the activities of the "Beyond Bias" project through my involvement as an intern. The aim was to analyze how the Human-centered design approach defined the problems affecting the quality of services for young people in Burkina Faso and what solutions they then developed to address these problems. Particular attention is paid to how providers and stakeholders of the project were involved in the process and how the proposed solutions take into account the challenges they face and their experiences. Through the description of situations in which the project actors were brought to interact and collaborate with local health providers, I describe the dynamics that rendered the exchanges with the stakeholders unproductive, thus highlighting the blockages at the level of the project actors that made it difficult for the designers to reconcile the solutions with the challenges encountered in practice by the providers and the priorities and restrictions put in place within the framework of the project.