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Therapeutic efficacy of antitumor dendritic cell vaccinations correlates with persistent Th1 responses, high intratumor CD8+ T cell recruitment and low relative regulatory T cell infiltration.

par Driessens, Grégory ;Gordower, Laurence ;Nuttin, Lise ;Stordeur, Patrick ;Blocklet, Didier ;Egrise, Dominique ;Velu, Thierry ;Bruyns, Catherine
Référence Cancer immunology and immunotherapy, 57, 12, page (1745-1756)
Publication Publié, 2008-12

Article révisé par les pairs

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Titre:	Therapeutic efficacy of antitumor dendritic cell vaccinations correlates with persistent Th1 responses, high intratumor CD8+ T cell recruitment and low relative regulatory T cell infiltration.
Auteur:	Driessens, Grégory; Gordower, Laurence; Nuttin, Lise; Stordeur, Patrick; Blocklet, Didier; Egrise, Dominique; Velu, Thierry; Bruyns, Catherine
Informations sur la publication:	Cancer immunology and immunotherapy, 57, 12, page (1745-1756)
Statut de publication:	Publié, 2008-12
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	T cells
	Tumor immunity
	Vaccination
MeSH keywords:	Animals
	Brain Neoplasms -- immunology -- therapy
	CD4-Positive T-Lymphocytes -- immunology
	CD8-Positive T-Lymphocytes -- immunology
	Cancer Vaccines -- immunology -- therapeutic use
	Cytotoxicity, Immunologic
	Dendritic Cells -- transplantation
	Gliosarcoma -- immunology -- therapy
	Granulocyte-Macrophage Colony-Stimulating Factor -- immunology -- metabolism
	Lymphocytes, Tumor-Infiltrating -- immunology
	Male
	Rats
	Rats, Inbred F344
	T-Lymphocytes, Regulatory -- immunology
	Th1 Cells -- immunology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0340-7004
	info:doi/10.1007/s00262-008-0500-y
	info:scp/52549090017
	info:pmid/18369621