par Van Saen, D;Goossens, Elise 
;Bourgain, C;Ferster, Alina ;Tournaye, H
Référence Human reproduction, 26, 2, page (282-293)
Publication Publié, 2011-02
;Bourgain, C;Ferster, Alina ;Tournaye, HRéférence Human reproduction, 26, 2, page (282-293)
Publication Publié, 2011-02
Article révisé par les pairs
| Résumé : | Grafting of frozen-thawed testicular tissue has been suggested as a novel fertility preservation method for patients undergoing gonadotoxic treatments. However, this technique still needs further optimization before any clinical application. So far, grafting of human testicular tissue has only been performed to the back skin of nude mice and has shown spermatogonial stem-cell survival and occasionally differentiation up to primary spermatocytes. In this study, orthotopic grafting to mouse testes was evaluated as an alternative, and the effect of freezing and the donor's age was studied. |
