Résumé : Methane sulphonyl chloride, thionyl chloride and p‐toluene sulphonyl chloride react with voachalotine (I) to give, in each case, the same cyclised dihydroindole compound: 2α‐hydroxy‐17‐desoxyvincamajine(VI). At room temperature the same reagents give with affinisine (II) the expected derivatives, but at 115° only one compound is obtained: 16B‐chloromethyl‐voachalotane (VII). These observations are discussed on the basis of known reaction mechanisms and of the structure of the two alkaloïds (I and II), used in this work. Copyright © 1965 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim