par Ingvarsson, S;Asker, C;Szpirer, Josiane ;Levan, Göran;Klein, George
Référence Somatic cell and molecular genetics, 14, 4, page (401-405)
Publication Publié, 1988-07
Référence Somatic cell and molecular genetics, 14, 4, page (401-405)
Publication Publié, 1988-07
Article révisé par les pairs
Résumé : | Activated forms of the protooncogene c-raf have been found to transform established lines of rodent fibroblasts after transfection with DNA from several human and rat tumors. Using Southern blot analysis of DNAs from rat x mouse somatic cell hybrids, we have mapped c-raf to rat chromosome 4. An exogenous sequence that was found juxtaposed to c-raf within transforming DNA originally derived from a rat hepatocellular carcinoma was localized to chromosome 13. |