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Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi.

par Islam, Mozaffarul Quamrul;Platz, A;Szpirer, Josiane ;Szpirer, Claude ;Levan, Göran;Mannervik, B
Référence Human genetics, 82, 4, page (338-342)
Publication Publié, 1989-07

Article révisé par les pairs

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Résumé :

The numerous human glutathione transferases may be divided into three classes, mu, alpha and pi. Using a panel of human-rodent somatic cell hybrids and DNA probes specific for each of the three classes, we have mapped a class mu gene to chromosome 3, a class alpha gene to chromosome 6 and a class pi gene to chromosome 11. The two latter assignments confirm earlier reports, whereas the assignment of the class mu gene represents a new addition to the human gene map.