par Dahlbäck, B;Hansson, C;Islam, Mozaffarul Quamrul;Szpirer, Josiane
;Szpirer, Claude
;Lundwall, A;Levan, Göran
Référence Somatic cell and molecular genetics, 14, 5, page (509-514)
Publication Publié, 1988-09


Référence Somatic cell and molecular genetics, 14, 5, page (509-514)
Publication Publié, 1988-09
Article révisé par les pairs
Résumé : | Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13. |