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Discrimination of yeast genes involved in methionine and phosphate metabolism on the basis of upstream motifs.

par Gonze, Didier ;Pinloche, Sylvie;Gascuel, Olivier;van Helden, Jacques
Référence Bioinformatics, 21, 17, page (3490-3500)
Publication Publié, 2005-09

Article révisé par les pairs

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Résumé :

In yeast, methionine and phosphate metabolism are regulated by the complexes Met4p/Met28p/Cbf1p and Pho4p, respectively. The binding sites for these factors share a common core CACGTG. We evaluate our capability to discriminate phosphate- and methionine-responding genes on the basis of putative regulatory elements, despite the similarity between Met4p/Met28p/Cbf1p and Pho4p consensus.