par Gielen, Marcel
Référence Coordination chemistry reviews, 151, page (41-51)
Publication Publié, 1996
Article révisé par les pairs
Résumé : An overview is given of the results of the in vitro screening against MCF-7, a mammary tumour, and WiDr, a colon carcinoma, of several series of organotin compounds synthesized in the Free University of Brussels. Many di- and triorganotin compounds exhibit very promising in vitro antitumour activities. Di-n-butyltin bis(2,5-dihydroxybenzoate) is as active as cisplatin in vivo against murine Colon 26 carcinoma.