• Citer

Sympathetic rhythmicity in cardiac transplant recipients.

par Van De Borne, Philippe ;Montano, Nicola;Narkiewicz, K;Degaute, J P;Oren, R;Pagani, Massimo;Somers, Virend Kristen
Référence Circulation, 99, 12, page (1606-1610)
Publication Publié, 1999-03

Article révisé par les pairs

• Détails
• Contenu

Résumé :

Variability of R-R interval and muscle sympathetic nerve activity (MSNA) occurs predominantly at a low frequency (LF, +/-0.1 Hz) and a high frequency (HF, +/-0.25 Hz) in normal humans. Increased sympathetic drive in normal humans is associated with an increased LF component of the R-R interval and MSNA. Patients with severe heart failure have high sympathetic activity but decreased or absent LF power of both R-R and MSNA. We tested the hypothesis that this dysfunction in autonomic modulation in heart failure can be reversed by heart transplantation.