par Naeije, Robert 
;Golstein Golaire, Jacqueline ;Clumeck, Nathan
Référence Clinical endocrinology, 8, 6, page (467-472)
Publication Publié, 1978-06
;Golstein Golaire, Jacqueline ;Clumeck, Nathan Référence Clinical endocrinology, 8, 6, page (467-472)
Publication Publié, 1978-06
Article révisé par les pairs
| Résumé : | The pituitary-thyroid axis was investigated in nineteen euthyroid patients with severe diabetic ketoacidosis. A ‘low T3 syndrome’ was found, with the following characteristics: lowered serum concentrations of triiodothyronine (T3), increased reverse triiodothyronine (rT3), slightly low thyroxine (T4), normal thyrotrophin (TSH), slightly increased triiodothyronine uptake (RT3U) values, and a blunted TSH response to thyrotrophin-releasing hormone (TRH). These disturbances in thyroid-function tests required several days good control of the diabetes to be corrected, at least partially. The data suggest the presence of an abnormal extrathyroidal T4 metabolism as well as a pituitary defect. Caution is recommended in the interpretation of thyroid-function tests during and several days after the treatment of diabetic ketoacidosis. |
