Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast cancer cell lines

Journé, Fabrice; Chaboteaux, Carole; Magne, Nicolas; Duvillier, Hugues; Laurent, Guy; Body, Jean-Jacques

doi:doi/10.1186/bcr1363

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Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast cancer cell lines

par Journé, Fabrice

;Chaboteaux, Carole

;Magne, Nicolas ;Duvillier, Hugues

;Laurent, Guy

;Body, Jean-Jacques

Référence Breast cancer research, 8, 1, R2
Publication Publié, 2005-12

Article révisé par les pairs

Résumé :

Bisphosphonates are inhibitors of osteoclast-mediated tumor-stimulated osteolysis, and they have become standard therapy for the management of bone metastases from breast cancer. These drugs can also directly induce growth inhibition and apoptosis of osteotropic cancer cells, including estrogen receptor-positive (ER+) breast cancer cells.

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