par Preiser, Jean-Charles 
;Vincent, Jean Louis
Référence Nutrition clinique et métabolisme, 14, 4, page (326-333)
Publication Publié, 2000
;Vincent, Jean Louis Référence Nutrition clinique et métabolisme, 14, 4, page (326-333)
Publication Publié, 2000
Article révisé par les pairs
| Résumé : | Multiple organ failure syndrome often complicates the course of critically ill patients. In various experimental models, several features of gut dysfunction have been incriminated in the pathogenesis of this syndrome. This work aims at reviewing the clinical data on gut dysfunction recorded in critically ill patients. An increase in gut permeability and an alteration in intestinal motility have been clearly demonstrated, white bacterial translocation, an immune dysfunction and mucosal hypoperfusion are suggested by indirect arguments. The respective rotes of these alterations in the pathogenesis of multiple organ failure syndrome remain to be clarified by further investigations. © 2000 Éditions scientifiques et médicales Elsevier SAS. |
