par Boschero, Antonio Carlos;Kawazu, Shoji;Duncan, George;Malaisse, Willy
Référence FEBS letters, 83, 1, page (151-154)
Publication Publié, 1977
Référence FEBS letters, 83, 1, page (151-154)
Publication Publié, 1977
Article révisé par les pairs
Résumé : | Data are presented which confirm and extend conclusions derived from previous experiments carried out with 86Rb+. They suggest that glucose, by reducing the permeability of the plasma membrane to effluent K+, increases the concentration of K+ in the islet cells and under steady-state conditions, reduces proportionally the fractional turnover rate of the cellular K+ pool. Glucose, however, does not increase the inflow-outflow rate of K+ into the islet cells. The mechanism by which glucose affects the permeability of the plasma membrane to effluent K+ remains to be elucidated. |