par Le Gac, Stéphane
;Rickling, Stéphane
;Gerbaux, Pascal;Defrancq, Eric;Moucheron, Cécile
;Kirsch-De Mesmaeker, Andrée 
Référence Angewandte Chemie, 48, 6, page (1122-1125)
Publication Publié, 2009




Référence Angewandte Chemie, 48, 6, page (1122-1125)
Publication Publié, 2009
Article révisé par les pairs
Résumé : | (Figure Presented) Self-destruction: Attachment of a photoreactive Ru II complex to a guanine-containing oligonucleotide has led to an innovative biomolecular tool for gene silencing studies. This conjugate can be selectively photo-cross-linked with its complementary strand but undergoes a self-inhibition (or "seppuku") process in the presence of a noncomplementary target (see picture), which is an attractive strategy to avoid undesired secondary photoeffects. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA. |