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Are syngeneic mouse tumor models still valuable experimental models in the field of anti-cancer drug discovery?

par Darro, Francis;Decaestecker, Christine ;Gaussin, Jean-François ;Mortier, Steven;Van Ginckel, Rob;Kiss, Robert
Référence International journal of oncology, 27, 3, page (607-616)
Publication Publié, 2005-09

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Titre:	Are syngeneic mouse tumor models still valuable experimental models in the field of anti-cancer drug discovery?
Auteur:	Darro, Francis; Decaestecker, Christine; Gaussin, Jean-François; Mortier, Steven; Van Ginckel, Rob; Kiss, Robert
Informations sur la publication:	International journal of oncology, 27, 3, page (607-616)
Statut de publication:	Publié, 2005-09
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Anti-cancer agent
	In vitro
	In vivo
	Metastasis
	Screening
	Syngeneic mouse model
MeSH keywords:	Animals
	Antineoplastic Agents -- therapeutic use
	Cell Line, Tumor
	Drug Screening Assays, Antitumor -- methods
	Drug Screening Assays, Antitumor -- statistics & numerical data
	Female
	Leukemia L1210 -- drug therapy
	Leukemia L1210 -- pathology
	Leukemia P388 -- drug therapy
	Leukemia P388 -- pathology
	Male
	Mammary Neoplasms, Experimental -- drug therapy
	Mammary Neoplasms, Experimental -- pathology
	Melanoma, Experimental -- drug therapy
	Melanoma, Experimental -- pathology
	Mice
	Mice, Inbred C57BL
	Mice, Inbred DBA
	Neoplasms, Experimental -- drug therapy
	Neoplasms, Experimental -- pathology
	Reproducibility of Results
Note générale:	Comparative Study
	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:1019-6439
	info:scp/24344434641
	info:pmid/16077908