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Methyl oleate modulates LIP2 expression in the lipolytic yeast Yarrowia lipolytica.

par Fickers, Patrick ;Destain, Jacqueline;Thonart, Philippe
Référence Biotechnology letters, 27, 22, page (1751-1754)
Publication Publié, 2005

Article révisé par les pairs

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Résumé :

Methyl oleate was used as a primary carbon source and as an alternative inducer for the production of an extracellular lipase, Lip2, in Y. lipolytica strain LgX64.81 grown in a 20-l bioreactor. The lipase-encoding gene, LIP2, was investigated during culture on methyl oleate using a pLIP2-LacZ reporter fusion and we provide evidence for the involvement of methyl oleate in its regulation.