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Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.

par Delaine, Tamara;Cumpstey, Ian;Ingrassia, Laurent ;Le Mercier, Marie ;Okechukwu, Paul;Leffler, Hakon;Kiss, Robert ;Nilsson, Ulf J
Référence Journal of medicinal chemistry, 51, 24, page (8109-8114)
Publication Publié, 2008-12

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Titre:	Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.
Auteur:	Delaine, Tamara; Cumpstey, Ian; Ingrassia, Laurent; Le Mercier, Marie; Okechukwu, Paul; Leffler, Hakon; Kiss, Robert; Nilsson, Ulf J
Informations sur la publication:	Journal of medicinal chemistry, 51, 24, page (8109-8114)
Statut de publication:	Publié, 2008-12
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Cell Line, Tumor
	Cell Movement
	Drug Design
	Drug Screening Assays, Antitumor
	Esters
	Galectins -- chemistry
	Humans
	Inhibitory Concentration 50
	Kinetics
	Lung Neoplasms -- therapy
	Male
	Models, Chemical
	Prostatic Neoplasms -- therapy
	Protein Structure, Tertiary
	Thiogalactosides -- chemistry
	Thiogalactosides -- metabolism
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0022-2623
	info:doi/10.1021/jm801077j
	info:pii/10.1021/jm801077j
	info:scp/58149100964
	info:pmid/19053747