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The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener.

par Dabrowski, Michael;Ashcroft, Frances M;Ashfield, Rebecca;Lebrun, Philippe ;Pirotte, Bernard;Egelbjerg, J;Hansen, John Bondo;Wahl, Philip
Référence Diabetes (New York, N.Y.), 51, 6, page (1896-1906)
Publication Publié, 2002-06

Article révisé par les pairs

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Titre:	The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener.
Auteur:	Dabrowski, Michael; Ashcroft, Frances M; Ashfield, Rebecca; Lebrun, Philippe; Pirotte, Bernard; Egelbjerg, J; Hansen, John Bondo; Wahl, Philip
Informations sur la publication:	Diabetes (New York, N.Y.), 51, 6, page (1896-1906)
Statut de publication:	Publié, 2002-06
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adenosine Triphosphate -- analogs & derivatives
	Adenosine Triphosphate -- pharmacology
	Animals
	Benzothiadiazines
	Binding Sites
	Cell Line
	Cell Membrane -- metabolism
	Diazoxide -- analogs & derivatives
	Diazoxide -- metabolism
	Diazoxide -- pharmacology
	Electric Conductivity
	Gene Expression
	Glyburide -- metabolism
	Hypoglycemic Agents -- metabolism
	Ion Channel Gating -- drug effects
	Mice
	Mutagenesis
	Oocytes -- metabolism
	Potassium Channels, Inwardly Rectifying -- drug effects
	Potassium Channels, Inwardly Rectifying -- genetics
	Rats
	Recombinant Fusion Proteins
	Transfection
	Tritium
	Xenopus laevis
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:pmid/12031979