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New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.

par Florence, Xavier ;Sebille, Sophie;de Tullio, Pascal;Lebrun, Philippe ;Pirotte, Bernard
Référence Bioorganic & medicinal chemistry, 17, 22, page (7723-7731)
Publication Publié, 2009-11

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Titre:	New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.
Auteur:	Florence, Xavier; Sebille, Sophie; de Tullio, Pascal; Lebrun, Philippe; Pirotte, Bernard
Informations sur la publication:	Bioorganic & medicinal chemistry, 17, 22, page (7723-7731)
Statut de publication:	Publié, 2009-11
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Benzopyran derivatives
	Cromakalim analogues
	KATP channels
	Potassium channel openers
MeSH keywords:	Adenosine Triphosphate -- metabolism
	Animals
	Benzopyrans -- chemical synthesis
	Benzopyrans -- chemistry
	Benzopyrans -- pharmacology
	Cromakalim -- chemistry
	Cromakalim -- pharmacology
	Diazoxide -- chemistry
	Diazoxide -- pharmacology
	Islets of Langerhans -- drug effects
	Islets of Langerhans -- metabolism
	Muscle, Smooth, Vascular -- drug effects
	Muscle, Smooth, Vascular -- metabolism
	Pinacidil -- chemistry
	Pinacidil -- pharmacology
	Potassium Channels -- agonists
	Potassium Channels -- metabolism
	Rats
	Rats, Wistar
	Stereoisomerism
	Structure-Activity Relationship
	Vasodilator Agents -- chemical synthesis
	Vasodilator Agents -- chemistry
	Vasodilator Agents -- pharmacology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0968-0896
	info:doi/10.1016/j.bmc.2009.09.041
	info:pii/S0968-0896(09)00893-1
	info:scp/71749086139
	info:pmid/19822435