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Three-dimensional quantitative structure-activity relationships of ATP-sensitive potassium (KATP) channel openers belonging to the 3-alkylamino-4H-1,2,4-benzo- and 3-alkylamino-4H-1,2,4-pyridothiadiazine 1,1-dioxide families.

par de Tullio, Pascal;Dupont, Léon ;Francotte, Pierre;Counerotte, Stéphane;Lebrun, Philippe ;Pirotte, Bernard
Référence Journal of medicinal chemistry, 49, 23, page (6779-6788)
Publication Publié, 2006-11

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Titre:	Three-dimensional quantitative structure-activity relationships of ATP-sensitive potassium (KATP) channel openers belonging to the 3-alkylamino-4H-1,2,4-benzo- and 3-alkylamino-4H-1,2,4-pyridothiadiazine 1,1-dioxide families.
Auteur:	de Tullio, Pascal; Dupont, Léon; Francotte, Pierre; Counerotte, Stéphane; Lebrun, Philippe; Pirotte, Bernard
Informations sur la publication:	Journal of medicinal chemistry, 49, 23, page (6779-6788)
Statut de publication:	Publié, 2006-11
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adenosine Triphosphate -- physiology
	Animals
	Aorta -- drug effects
	Aorta -- physiology
	Cyclic S-Oxides -- chemistry
	Cyclic S-Oxides -- pharmacology
	Insulin -- secretion
	Ion Channel Gating
	Islets of Langerhans -- drug effects
	Islets of Langerhans -- secretion
	Models, Molecular
	Muscle Contraction -- drug effects
	Muscle, Smooth, Vascular -- drug effects
	Muscle, Smooth, Vascular -- physiology
	Potassium Channels -- chemistry
	Pyridines -- chemistry
	Pyridines -- pharmacology
	Quantitative Structure-Activity Relationship
	Rats
	Thiadiazines -- chemistry
	Thiadiazines -- pharmacology
Note générale:	In Vitro
	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0022-2623
	info:doi/10.1021/jm060534w
	info:scp/33751006447
	info:pmid/17154508