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2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers?

par Ouedraogo, Raogo;Becker, Bénédicte ;Boverie, Stéphane;Somers, Fabian;Antoine, Marie-Hélène ;Pirotte, Bernard;Lebrun, Philippe ;de Tullio, Pascal
Référence Biological chemistry, 383, 11, page (1759-1768)
Publication Publié, 2002-11

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Titre:	2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers?
Auteur:	Ouedraogo, Raogo; Becker, Bénédicte; Boverie, Stéphane; Somers, Fabian; Antoine, Marie-Hélène; Pirotte, Bernard; Lebrun, Philippe; de Tullio, Pascal
Informations sur la publication:	Biological chemistry, 383, 11, page (1759-1768)
Statut de publication:	Publié, 2002-11
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	BPDZ 44
	BPDZ 73
	Inhibition of insulin release
	Potassium channel openers
	Vasorelaxant activity
MeSH keywords:	ATP-Binding Cassette Transporters
	Alkanes -- chemical synthesis
	Alkanes -- pharmacology
	Animals
	Aorta, Thoracic -- drug effects
	Calcium Channel Blockers -- chemical synthesis
	Calcium Channel Blockers -- pharmacology
	Diazoxide -- chemical synthesis
	Diazoxide -- pharmacology
	Indicators and Reagents
	Insulin -- metabolism
	Islets of Langerhans -- drug effects
	Islets of Langerhans -- metabolism
	Muscle Contraction -- drug effects
	Muscle, Smooth, Vascular -- drug effects
	Potassium Channels -- agonists
	Potassium Channels, Inwardly Rectifying
	Rats
	Rats, Wistar
	Structure-Activity Relationship
	Thiadiazines -- chemical synthesis
	Thiadiazines -- pharmacology
Note générale:	In Vitro
	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:1431-6730
	info:doi/10.1515/BC.2002.197
	info:scp/0036869615
	info:pmid/12530541