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The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation.

par Cnop, Miriam ;Hughes, S J;Igoillo Esteve, Mariana ;Hoppa, M B;Sayyed, F;van de Laar, L;Gunter, J H;de Koning, E J P;Walls, G V;Gray, D W G;Johnson, P R V;Hansen, B C;Morris, J F;Pipeleers-Marichal, M;Cnop, I;Clark, A.
Référence Diabetologia, 53, 2, page (321-330)
Publication Publié, 2010

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Titre:	The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation.
Auteur:	Cnop, Miriam; Hughes, S J; Igoillo Esteve, Mariana; Hoppa, M B; Sayyed, F; van de Laar, L; Gunter, J H; de Koning, E J P; Walls, G V; Gray, D W G; Johnson, P R V; Hansen, B C; Morris, J F; Pipeleers-Marichal, M; Cnop, I; Clark, A.
Informations sur la publication:	Diabetologia, 53, 2, page (321-330)
Statut de publication:	Publié, 2010
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adult
	Age Distribution
	Aging -- physiology
	Animals
	Biological Markers -- metabolism
	Cause of Death
	Cell Division
	Diabetes Mellitus, Type 2 -- pathology
	Humans
	Insulin-Secreting Cells -- cytology
	Insulin-Secreting Cells -- pathology
	Insulin-Secreting Cells -- physiology
	Lipofuscin -- metabolism
	Macaca mulatta
	Mice
	Mice, Inbred C57BL
	Models, Theoretical
	Pancreas -- cytology
	Pancreas -- pathology
	Tissue Donors
Note générale:	Journal Article
	Research Support, N.I.H., Extramural
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0012-186X
	info:doi/10.1007/s00125-009-1562-x
	info:scp/77949289481
	info:pmid/19855953