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Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency.

par Critchfield, J W;Ho, O;Roberts, Mary;Van Lint, Carine ;Verdin, Eric ;Butera, S T
Référence Antiviral chemistry & chemotherapy, 10, 5, page (275-284)
Publication Publié, 1999

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Titre:	Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency.
Auteur:	Critchfield, J W; Ho, O; Roberts, Mary; Van Lint, Carine; Verdin, Eric; Butera, S T
Informations sur la publication:	Antiviral chemistry & chemotherapy, 10, 5, page (275-284)
Statut de publication:	Publié, 1999
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine -- pharmacology
	Anti-HIV Agents -- pharmacology
	Chromatin -- genetics
	Chromatin -- physiology
	Enzyme Inhibitors -- pharmacology
	HIV Infections -- drug therapy
	HIV Infections -- virology
	HIV-1 -- drug effects
	HIV-1 -- genetics
	HIV-1 -- growth & development
	HIV-1 -- physiology
	HL-60 Cells -- metabolism
	HL-60 Cells -- virology
	Humans
	Isoquinolines -- pharmacology
	NF-kappa B -- antagonists & inhibitors
	NF-kappa B -- physiology
	Protein Kinase Inhibitors
	RNA, Viral -- drug effects
	RNA, Viral -- genetics
	Sulfonamides -- pharmacology
	Transcription, Genetic -- drug effects
	Tumor Necrosis Factor-alpha -- pharmacology
	Virus Activation -- drug effects
	Virus Activation -- genetics
	Virus Latency -- drug effects
	Virus Latency -- genetics
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0956-3202
	info:scp/0032843282
	info:pmid/10574182