Translational control mediated by UA-rich sequences.

Kruys, Véronique; Beutler, Bruce; Huez, Georges

Recherche avancée | Historique de recherche Mon DI-fusion | À propos de DI-fusion | Contact |

Citer

Translational control mediated by UA-rich sequences.

par Kruys, Véronique

;Beutler, Bruce ;Huez, Georges

Référence Enzyme, 44, 1-4, page (193-202)
Publication Publié, 1990

Article révisé par les pairs

Résumé :

Several messenger RNAs coding for cytokines, growth factors or oncoproteins contain a conserved UA-rich sequence in their 3' untranslated regions. This sequence, which is composed of several interspersed repeats of the octanucleotide UUAUUUAU, is a key element in the posttranscriptional regulation of these mRNAs. Previously shown to be involved in mRNA destabilization, these UA-rich elements can also strongly influence mRNA translation. A translation inhibition mediated by these sequences has indeed been observed in vitro as well as in frog oocyte or in somatic cells.

Documents en relation

DI-fusion

The Bacillus subtilis ywbD gene encodes RlmQ, the 23S rRNA methyltransferase forming m7G2574 in the A-site of the peptidyl transferase center.
par Wolff, Philippe , Labar, Geoffray , Lechner, Antony , Van Elder, Dany , Soin, Romuald , Gueydan, Cyril , Kruys, Véronique , Droogmans, Louis , Roovers, Martine
Publication 2023-12-01
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga
par Moris, Victoria , Bruneau, Lucie , Berthe, Jérémy , Heuskin, Anne-Catherine , Penninckx, Sébastien , Ritter, Sylvia , Weber, Uli , Durante, Marco , Danchin, Etienne E.G.J. , Hespeels, Boris , Doninck, Karine Van
Publication 2024-12
ASO Author Reflections: Histological Growth Patterns of Colorectal Peritoneal Metastases Significantly Affect Prognosis in Patients Presenting for Curative-Intent Cytoreductive Surgery.
par El Asmar, Antoine , Kamdem, Leonel , Khaled, Charif , Liberale, Gabriel
Publication 2024-03
Engineered Wnt7a ligands rescue blood–brain barrier and cognitive deficits in a COVID-19 mouse model
par Trevino, Troy , Fogel, Avital , Otkiran, Guliz , Niladhuri, Seshadri , Sanborn, Mark , Class, Jacob , Almousawi, Ali , Vanhollebeke, Benoît , Tai, Leon M , Rehman, Jalees , Richner, Justin M , Lutz, Sarah E
Publication 2024-02-01
pycofitness—Evaluating the fitness landscape of RNA and protein sequences
par Pucci, Fabrizio , Zerihun, Mehari B , Rooman, Marianne , Schug, Alexander
Publication 2024-02-01

Référencement	Visibilité	Pérennité	Facilité
Les publications encodées constituent la bibliographie académique de l'Université.	Les documents déposés sont indexés par les moteurs de recherche (Google Scholar,…).	Les documents déposés en open-access sont archivés au sein du réseau de préservation SAFE-PLN (www.safepln.org).	Les listes de publications sont compatibles avec le CV-ULB, le FNRS et accessibles sur le web.