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A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir.

par Shand, N.;Weber, F;Mariani, Luigi;Bernstein, Mark;Gianella-Borradori, Athos;Long, Z.;Sorensen, AG;Barbier, Nicolas Serge ;GLI328 European-canadian study group,
Référence Human gene therapy, 10, 14, page (2325-2335)
Publication Publié, 1999-09

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Titre:	A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir.
Auteur:	Shand, N.; Weber, F; Mariani, Luigi; Bernstein, Mark; Gianella-Borradori, Athos; Long, Z.; Sorensen, AG; Barbier, Nicolas Serge; GLI328 European-canadian study group,
Informations sur la publication:	Human gene therapy, 10, 14, page (2325-2335)
Statut de publication:	Publié, 1999-09
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adult
	Aged
	Antiviral Agents -- therapeutic use
	Brain -- pathology
	Brain -- surgery
	Brain Neoplasms -- surgery
	Brain Neoplasms -- therapy
	Combined Modality Therapy
	Female
	Ganciclovir -- therapeutic use
	Gene Therapy
	Glioblastoma -- surgery
	Glioblastoma -- therapy
	Humans
	Magnetic Resonance Imaging
	Male
	Middle Aged
	Neoplasm Recurrence, Local
	Simplexvirus -- enzymology
	Simplexvirus -- genetics
	Survival Analysis
	Thymidine Kinase -- genetics
Note générale:	Clinical Trial
	Clinical Trial, Phase I
	Clinical Trial, Phase II
	Journal Article
	Multicenter Study
Langue:	Anglais
Identificateurs:	urn:issn:1043-0342
	info:doi/10.1089/10430349950016979
	info:pmid/10515452