par Eizirik, Decio L. 
;Monteiro, C M;Voltarelli, J C;Foss, M C
Référence Brazilian journal of medical and biological research, 20, 5, page (533-537)
Publication Publié, 1987
;Monteiro, C M;Voltarelli, J C;Foss, M CRéférence Brazilian journal of medical and biological research, 20, 5, page (533-537)
Publication Publié, 1987
Article révisé par les pairs
| Résumé : | 1. Sixty-five Brazilian, patients with type I, insulin-dependent diabetes mellitus (IDDM) and 100 unaffected individuals were typed for HLA-A, -B, -C and DR antigens. 2. A significantly higher frequency of HLA-A2 (48% of the patients versus 21% of the controls), B15 (20% of the controls), DR3 (57% of the patients versus 28% of the controls) and DR4 (54% of the patients versus 23% of the controls) was found for IDDM patients compared to the controls. 3. In contrast, DR2 (11% of the patients versus 31% of the controls) and DR7 (3% of the patients versus 21% of the controls) were lower in diabetics, but the difference was not significant. 4. The data reported here, when compared with those of other studies, emphasize the ethnic variability in HLA-IDDM associations. |
