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Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease.

par Braun, Michel Y ;Lowin, B;French, L;Acha-Orbea, Hans;Tschopp, J
Référence The Journal of experimental medicine, 183, 2, page (657-661)
Publication Publié, 1996-02

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Titre:	Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease.
Auteur:	Braun, Michel Y; Lowin, B; French, L; Acha-Orbea, Hans; Tschopp, J
Informations sur la publication:	The Journal of experimental medicine, 183, 2, page (657-661)
Statut de publication:	Publié, 1996-02
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Base Sequence
	Cytotoxicity, Immunologic -- genetics
	Fas Ligand Protein
	Female
	Flow Cytometry
	Graft vs Host Disease -- etiology
	Graft vs Host Disease -- immunology
	Graft vs Host Disease -- mortality
	Graft vs Host Disease -- pathology
	Membrane Glycoproteins -- deficiency
	Membrane Glycoproteins -- genetics
	Mice
	Mice, Inbred C57BL
	Mice, Knockout
	Molecular Sequence Data
	Perforin
	Pore Forming Cytotoxic Proteins
	Spleen -- cytology
	Spleen -- immunology
	Survival Analysis
	T-Lymphocytes, Cytotoxic -- immunology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0022-1007
	info:pmid/8627178
	PMC2192472