• SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signaling.
Auteur:Wang, Yue; Keogh, Rosemary J; Hunter, Melissa G; Mitchell, Christina A; Frey, Randall S; Javaid, Kamran; Malik, Asrar B; Schurmans, Stéphane; Tridandapani, Susheela; Marsh, Clay B
Informations sur la publication:The Journal of immunology, 173, 11, page (6820-6830)
Statut de publication:Publié, 2004-12
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Cell Line
Cell Membrane -- immunology
Cell Membrane -- metabolism
Cells, Cultured
Contractile Proteins -- metabolism
Macrophage Colony-Stimulating Factor -- metabolism
Macrophage Colony-Stimulating Factor -- physiology
Macrophages -- immunology
Macrophages -- metabolism
Mice, Inbred C57BL
Mice, Knockout
Microfilament Proteins -- metabolism
Monocytes -- immunology
Monocytes -- metabolism
NF-kappa B -- antagonists & inhibitors
NF-kappa B -- genetics
NIH 3T3 Cells
Phosphoric Monoester Hydrolases -- deficiency
Phosphoric Monoester Hydrolases -- genetics
Phosphoric Monoester Hydrolases -- metabolism
Phosphoric Monoester Hydrolases -- physiology
Proline -- metabolism
Protein Binding
Protein Structure, Tertiary -- physiology
Protein Transport -- immunology
Protein-Serine-Threonine Kinases -- antagonists & inhibitors
Protein-Serine-Threonine Kinases -- metabolism
Proto-Oncogene Proteins -- antagonists & inhibitors
Proto-Oncogene Proteins -- metabolism
Proto-Oncogene Proteins c-akt
Receptor, Macrophage Colony-Stimulating Factor -- metabolism
Signal Transduction -- immunology
Tyrosine -- metabolism
src Homology Domains -- physiology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.