Titre:
  • Cannabinoids inhibit neurodegeneration in models of multiple sclerosis.
Auteur:Pryce, Gareth; Ahmed, Zubair; Hankey, Deborah J R; Jackson, Samuel J; Croxford, J Ludovic; Pocock, Jennifer M; Ledent, Catherine; Petzold, Axel; Thompson, Alan J; Giovannoni, Gavin; Cuzner, M Louise; Baker, David
Informations sur la publication:Brain, 126, Pt 10, page (2191-2202)
Statut de publication:Publié, 2003-10
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Cannabinoids
Excitotoxicity
Experimental allergic encephalomyelitis
Multiple sclerosis
Neuroprotection
MeSH keywords:Animals
Aspartic Acid -- analogs & derivatives
Aspartic Acid -- analysis
Axons -- chemistry
Axons -- pathology
Benzoxazines
Cannabinoids -- therapeutic use
Cyclohexanols -- therapeutic use
Dizocilpine Maleate -- therapeutic use
Encephalomyelitis, Autoimmune, Experimental
Excitatory Amino Acid Agonists -- therapeutic use
Gene Deletion
Humans
Mice
Mice, Transgenic
Monomeric GTP-Binding Proteins -- genetics
Morpholines -- therapeutic use
Multiple Sclerosis -- drug therapy
Multiple Sclerosis -- pathology
N-Methylaspartate -- therapeutic use
Naphthalenes -- therapeutic use
Nerve Degeneration
Nuclear Proteins -- genetics
Receptors, Cannabinoid
Receptors, Drug -- agonists
Receptors, N-Methyl-D-Aspartate -- antagonists & inhibitors
Retina -- drug effects
Retina -- pathology
Saccharomyces cerevisiae Proteins
Spinal Cord -- pathology
Uveitis -- immunology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0006-8950
info:doi/10.1093/brain/awg224
info:pii/awg224
info:scp/0242304878
info:pmid/12876144