Titre:
  • Enhanced morphine withdrawal and micro -opioid receptor G-protein coupling in A2A adenosine receptor knockout mice
Auteur:Bailey, Alexis; Davis, Lianne; Lesscher, Heidi M B; Kelly, Mary; Ledent, Catherine; Hourani, Susanna; Kitchen, Ian
Informations sur la publication:Journal of neurochemistry, 88, 4, page (827-834)
Statut de publication:Publié, 2004-02
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Analysis of Variance
Animals
Autoradiography -- methods
Behavior, Animal -- drug effects
Binding Sites
Brain -- anatomy & histology
Brain -- drug effects
Brain -- metabolism
Densitometry -- methods
Diarrhea -- chemically induced
Dose-Response Relationship, Drug
Drug Interactions
Enkephalin, Ala(2)-MePhe(4)-Gly(5)- -- pharmacokinetics
GTP-Binding Proteins -- metabolism
Guanosine 5'-O-(3-Thiotriphosphate) -- pharmacokinetics
Male
Mice
Mice, Knockout
Morphine -- adverse effects
Motor Activity -- drug effects
Naloxone -- therapeutic use
Narcotic Antagonists
Raclopride -- pharmacokinetics
Receptor, Adenosine A2A -- genetics
Receptor, Adenosine A2A -- metabolism
Receptors, Opioid, mu -- metabolism
Substance Withdrawal Syndrome -- drug therapy
Substance Withdrawal Syndrome -- physiopathology
Sulfur Isotopes -- pharmacokinetics
Tremor -- chemically induced
Tremor -- drug therapy
Tritium -- pharmacokinetics
Urine -- physiology
Weight Loss -- drug effects
Note générale:Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
FLWIN
Langue:Anglais
Identificateurs:urn:issn:0022-3042
info:doi/10.1046/j.1471-4159.2003.02214.x
info:pii/2214
info:pmid/14756803