Article révisé par les pairs
Titre:
  • Phosphorylated HER-2 tyrosine kinase and Her-2/neu gene amplification as predictive factors of response to trastuzumab in patients with HER-2 overexpressing metastatic breast cancer (MBC).
Auteur:Giuliani, Rosa; Durbecq, Virginie; Di Leo, Angelo; Paesmans, Marianne; Larsimont, Denis; Leroy, Jean-Yves; Borms, Marleen; Vindevoghel, Anita; Jerusalem, Guy; D'Hondt, Veronique; Dirix, Luc Y; Canon, Jean-Luc; Richard, Vincent; Cocquyt, Veronique; Majois, Françoise; Reginster, Michel; Demol, Jan; Kains, Jean-Pierre; Delree, Paul; Keppens, Carine; Sotiriou, Christos; Piccart-Gebhart, Martine; Cardoso, Fatima
Informations sur la publication:European journal of cancer, 43, 4, page (725-735)
Statut de publication:Publié, 2007-03
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Metastatic breast cancer
Phosphorylated HER-2
Predictive factors
Trastuzumab
MeSH keywords:Antibodies, Monoclonal -- therapeutic use
Antineoplastic Agents -- therapeutic use
Breast Neoplasms -- drug therapy
Breast Neoplasms -- genetics
Female
Gene Amplification
Genes, erbB-2 -- genetics
Humans
In Situ Hybridization, Fluorescence
Neoplasm Metastasis
Phosphorylation
Protein-Tyrosine Kinases -- genetics
Protein-Tyrosine Kinases -- metabolism
Receptor, erbB-2 -- metabolism
Retrospective Studies
Treatment Outcome
Note générale:Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0959-8049
info:doi/10.1016/j.ejca.2006.11.019
info:pii/S0959-8049(06)01065-3
info:scp/34047123086
info:pmid/17251007

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