Résumé : The treated water Biodegradable Organic Matter (BOM) content is one of the main factors controlling bacterial regrowth in Distribution Systems (DS). This paper presents an approach to predicting regrowth potential with the objective of helping utilities in the preliminary selection of alternative treatment scenarios. The proposed approach comprises four phases: (i) applying, at bench scale, different types of treatment to a raw water to obtain treated waters to be tested for their regrowth potential; (ii) applying an experimental procedure to the various treated waters which consists of the study of bacterial growth during a Biodegradable Dissolved Organic Carbon (BDOC) test; (iii) partitioning BDOC into three classes of various biodegradability compounds by fitting the bacterial growth curve with a biodegradation model; (iv) using the BDOC and partitioning data to simulate bacterial growth in a DS with a model describing bacterial dynamics in the DS. The various phases of the approach are detailed using a case study for which different types of treatments were tested.