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Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer.

par Siu, Lillian L;Awada, Ahmad ;Takimoto, Chris H;Piccart-Gebhart, Martine ;Schwartz, Brian;Giannaris, Tom;Lathia, Chetan;Petrenciuc, Oana;Moore, Malcolm J
Référence Clinical cancer research, 12, 1, page (144-151)
Publication Publié, 2006-01

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Titre:	Phase I trial of sorafenib and gemcitabine in advanced solid tumors with an expanded cohort in advanced pancreatic cancer.
Auteur:	Siu, Lillian L; Awada, Ahmad; Takimoto, Chris H; Piccart-Gebhart, Martine; Schwartz, Brian; Giannaris, Tom; Lathia, Chetan; Petrenciuc, Oana; Moore, Malcolm J
Informations sur la publication:	Clinical cancer research, 12, 1, page (144-151)
Statut de publication:	Publié, 2006-01
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adult
	Aged
	Aged, 80 and over
	Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
	Benzenesulfonates -- pharmacokinetics
	Benzenesulfonates -- therapeutic use
	Deoxycytidine -- analogs & derivatives
	Deoxycytidine -- pharmacokinetics
	Deoxycytidine -- therapeutic use
	Dose-Response Relationship, Drug
	Drug Interactions
	Female
	Humans
	Male
	Maximum Tolerated Dose
	Middle Aged
	Neoplasms -- drug therapy
	Pancreatic Neoplasms -- drug therapy
	Pyridines -- pharmacokinetics
	Pyridines -- therapeutic use
Note générale:	Clinical Trial, Phase I
	Journal Article
	Multicenter Study
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:1078-0432
	info:doi/10.1158/1078-0432.CCR-05-1571
	info:pii/12/1/144
	info:scp/31544460436
	info:pmid/16397036